Beatriz [Salma Hayek] — an immigrant from a poor town in Mexico, has drawn on her innate kindness to build a career as a spiritual health practitioner in Los Angeles. Doug Strutt [John Lithgow] is a cutthroat, self-satisfied billionaire real estate developer. When these two opposites meet at a dinner party, their worlds collide and neither will ever be the same.
ME AND EARL AND THE DYING GIRL is the uniquely funny, moving story of Greg [Thomas Mann], a high school senior who is trying to blend in anonymously, avoiding deeper relationships as a survival strategy for navigating the social minefield that is teenage life. He even describes his constant companion Earl [RJ Cyler], with whom he makes short film parodies of classic movies, as more of a “co-worker” than a best friend. But when Greg’s mom [Connie Britton] insists he spend time with Rachel [Olivia Cooke] – a girl in his class who has just been diagnosed with cancer – he slowly discovers how worthwhile the true bonds of friendship can be.